Acrylic can contain vinyl acetate (been found to be possibly carcinogenic to humans) or methyl acrylate (may cause liver and kidney damage).
How much of toxic compounds are released once the product is in its solid form? If it isn't accumulative and doesn't bind to anything I wouldn't be very concerned. Liver and kidneys are used to dealing with toxic substances.
Carcinogens are not my main concern (since almost anything can be carcinogenic in some form) but endocrine disruptors are. Human endocrine system is quite vulnerable to outside factors. There is a difference in something being toxic in high amounts and something having hormonal effect at any dose. Whether the effect is observable in practice is of course another matter. But if it binds to estrogen receptors then it is already having some effect, whether the person notices it or not.
At least acrylic is used in medical prosthetics and dental applications so it should be fairly safe (nobody would put PVC for example in human body). Vulcanite is my main choice though. Vulcanite is also the most pleasing in mouth and looks better.