Oh man, I remember my first nic hit. It wasn't even with normal American or European style tobacco. I was about 16 or 17 and had been smoking herb for a while and thought I could hit a pipe. I had friends that recently visited their Dad working in Dubai and they had brought back some of the traditional tobacco from the region called "dokha". It's a unique strain that isn't fermented and aged and has a really low moisture content and is essentially ground up. It's smoke out of a little pipe called a medwakh and leaves a instant buzz called a "laf raas" or head spin in Arabic.
Being young and curious I asked if I could take puff. Only I didn't puff on it. I took a long and deep drag and held for a few seconds before coughing it out. What ensued next I will never forget. It took a second to kick in but hit me like a ton of bricks. I had such a strong spin I literally had to lay on a bed looking up for what seemed to be at least five minute. I felt my eyes fluttering and my whole body had an intense tingle. After 5 minutes or so I got up and asked my buddy "hey man, think I could get another one of those?"
Needless to although being very intense, I certainly enjoyed it. Dokha feels very differently than other tobaccos. Not really sure what it is about it. The buzz is much more in the head than in the stomach without the nausea. When I would inhale cigarettes or rolling tobacco it was a much heavier almost "sick to the stomach" kind of sensation.