I have to say Depp is a good actor. He was really good in Edward Scissor Hands, What's Eating Gilbert Grape, Blow, Sleepy Hollow, Sweeney Todd, Don Juan DeMarco, Public Enemies, Alice In Wonderland, the Pirates movies, The Tourist, and Rango. That's an impressive body of work.
Also into Mark Wahlberg, Liam Neeson, Morgan Freeman, Edward Norton, Jeremy Brett (he WAS Holmes!) and David Suchet (he WAS Poirot!).
As for actresses I like Amy Adams, Drew Barrymore, Anne Hathaway, Goldie Hawn, Helen Mirren, Meryl Streep, and Glenn Close.