I have two blends that I tinker with. Both of them are creations that originated with John Dengler and my father and me.
Of the those two blends, I've learned to tweak them even more using Sutliff Virgina Slices mixed with Black Cavendish with Green River as a replacement for Lane RLP-6.
The Virginia Slices give a deeper and more true note and when mixed with black Cavendish, the aromatic balance makes them even more enjoyable.
I tend not to create too many "different" blends for the simple reason that pipe smoking for me is "comfort" food.