May I suggest Henry IV, Parts 1 & 2, with Falstaff, Shakespeare's greatest character (a loveable wretch of a fallen knight), and some great speech-ifying.
Or if you're in a bloody mood, Titus Andronicus, more gruesome than any Freddie Krueger (sp?) or "chainsaw massacre" film ever made. Well, it grossed me out anyway.
Or, if you're up for something like science fiction, of a sort, try his farewell to the stage: The Tempest. (An allegorial commentary on exploration and colonization.)
It's interesting that while Shakespeare wrote in the late 1500's - early 1600's, I can't recall any mention of tobacco use.