I don't see the point. It's going to interrupt the flavors of your pipe tobacco, and cause you to salivate more leading to a wet gurgly smoke. If you're doing it for the nicotine and your not getting enough from your pipe tobacco, try a pipe tobacco with a higher nicotine content. Macbarren just released a new one today called Bold Kentucky. Apparently it's chock full of dark fired kentucky burley so should be a heavy nic blend. Using snuss or chew, or dip, or anything else like that however, while smoking, is just beyond me. Spit that stuff out man, and enjoy your pipe.