There is no such thing "what is best".. Somebody may tell you what works for them, and after you try it you would argue that they were wrong. The beauty of pipe smoking is that there are no actual rules, do what you feel like, experiment, and most importantly stick to what YOU like and what works best for YOU. Sure, we could offer some tips and tricks, share our experience with you, but at the end of the day what is best means what works for you and you alone - and there is only one way to find that out - give it a try.
That being said, I personally prefer flake in a large bowl, for example a no 4 pot, or a 320 shape style by Savinelli. I dedicate a pipe for aromatics, one for virginias, one for virginia burley and another for va/per. I also keep a few pipes dedicated to English or Balkans, and I have one stinky pipe in which I love my laklands. I drink whatever suits me on the spot, but I do like coffee or tea most, mineral water works sometimes with a bit of syrup. I rarely combine a pipe with alcohol, mostly if I have wine left after a hearty dinner I do accompany it with a pipe, perhaps even pour another after I finish it. This is what I like, and I like it this way today, no guarantees my tastes won't change down the road. The guys will share what they like, as the same applies to everybody, this you need to experiment and see what you like.