This guy smoked Rustica straight and inhaled it:
I began to feel a blissful clarity, an acuity that I had never felt from tobacco before. I looked around me, and up into the elm branches and the wispy cirrus clouds in the sky, and was very pleased. Everything was more real, and very nice. My vision was 'larger', and brighter. I also became a little nauseous, but I think water would have helped with that. I got on the rope swing that hangs from the elm, and enjoyed life quite a bit for a few minutes. The blissful clarity subsided rather quickly, but it is conducive, I think, to a mindset that could be very good, at least if used in moderation.
https://www.erowid.org/experiences/exp.php?ID=28978