It is well documented that pipe smoking does indeed reduce an individuals ability to resist two tobacco-related afflictions. Although not everyone is affected by these ailments, the symptoms of these diseases can, in end-stage scenarios, be personally and financially devastating. Further research is needed, but frankly, it is difficult to pry research dollars out of the government for ailments that only affect pipe smokers. We refer to these conditions as "Orphan Diseases", and if you ever seen an orphan with a pipe, you would know how truly heartbreaking PAD and TAD can be.