With a major change to an industry-wide due diligence program, the Sustainable Tobacco Program (STP), now at least 180 tobacco companies are pledging to prohibit all children under 18 from handling green tobacco on farms in their supply chains.
...We have consistently found that many children who handle tobacco are at serious risk of nicotine poisoning, also known as Green Tobacco Sickness, an illness caused by absorption of nicotine through the skin, which can cause vomiting, nausea, dizziness, headaches, loss of appetite, and insomnia. The long-term effects of absorbing nicotine through the skin are unknown; the dangers of nicotine exposure through smoking are well-known and serious.
https://www.hrw.org/news/2017/11/15/tobacco-companies-commit-protect-child-workers-worldwide